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    Breakfast included
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    Check In: 3:00 PM  |  Check Out: 12:00 PM

    Houston Medical Center

      8080 S Main Street, Houston
      (Includes VAT)
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      Welcome to Holiday Inn Express & Suites Houston Medical Center

      Guests Love Houston Hotel's Free Medical Center Shuttle

      Searching for Houston, Texas Medical Center hotels? Look no further than the Holiday Inn Express® & Suites Houston Medical Center hotel, which is thoughtfully located just moments from the hospital campus. You can easily access the Museum and Theater District in downtown Houston with the hotel's central location off Hwy-90.

      Medical specialists, hospital patients and their families all appreciate the hotel's proximity to MD Anderson, Memorial Hermann, Baylor College of Medicine, Texas Children's and St. Luke's hospitals. Another perk for visitors in Houston, Texas is the Medical Center shuttle. The hotel's free shuttle runs to the area hospitals and Reliant Park.

      Our central location close to the Houston Zoo and other downtown attractions, including the Rice Village shopping center, provides you with endless opportunities for entertainment during your visit. Reliant Stadium, just across the street, is North America's largest event complex, so you can rest assured there is always an exciting event to check out nearby.

      Stay smart and eat smart every morning when you stay at the Holiday Inn Express® & Suites Houston Medical Center hotel with the free Express Start breakfast bar, which offers our signature, cinnamon rolls. If you indulge a little too much on great Texas barbecue, visit the on-site Fitness Center. Book your reservations in Houston, Texas today and start relaxing.

      Features From free parking to free Wi-Fi access to free breakfast, we make affordability a priority. With businesses and attractions like Reliant Park nearby, our hotel's guests benefit from the location, too.

      Business Services

      Courier Service
      Secretarial Services
      Wireless Data Connection
      Business Center

      Health and Fitness Center (On-site)

      Health/Fitness Center On-Site

      Housekeeping and Laundry Services

      Daily Housekeeping

      Dry Cleaning Pickup or Laundry Valet

      Same Day Dry Cleaning


      Safety Deposit Box available at Front Desk

      Wake up to the tempting aroma of fresh 100% Arabica bean coffee, and let your nose lead you to the delicious selections at the free, hot Express Start breakfast bar. From gooey signature cinnamon rolls to eggs, meats and more, we have all your favorites.

      Nearby Restaurants

      Olive Garden
      Location:  Not Located on Property
      Serves:  Lunch, Dinner
      As part of that commitment, they serve fresh, delicious Italian food served in a comfortable setting where everyone is welcomed as a member of their family.
      Marco's Mexican Restaurant
      Location:  Restaurant not on site.
      Serves:  Lunch, Dinner
      Some of Houston's best Mexican food and margaritas. Within walking distance to hotel.
      Location:  Not on property
      Serves:  Lunch, Dinner
      Some of the very best Seafood in town.
      Location:  Off Site.
      Serves:  Lunch, Dinner
      Mexican food of the highest quality
      Joe's Crab Shack
      Location:  not located in hotel
      Serves:  Lunch, Dinner
      Luther's Bar-B-Que
      Location:  Not located in hotel
      Serves:  Lunch, Dinner
      Sarpino's Pizza
      Location:  Not in hotel
      Serves:  Lunch, Dinner
      Classic Italian Pizza and Food. High quality sauces and spices. There are plenty of reasons this is one of the best places in town for authentic Italian Pizza. You may pay a little more than at their competitors, but there is simply no comparison to large brand pizza. Try the pizza package. Save some money, and get the only Pizza endorsed by our employees.

      Guestroom data services

      Wireless Data Connection

      High-speed Internet Access

      Business Center data services

      Wireless Data Connection

      High-speed Internet Access

      Public space data services

      Wireless Data Connection

      High-speed Internet Access

      • Car Parking Available
      • This facility has a large number of Medical Guests. Our concern for their health has led us to restrict pets to those that provide a verifiable medical service. If non service pets are found we will asses a 250 fine and evict. No refund will be given.
      • American Express
      • Carte Blanche
      • Diners Club
      • Discover
      • JCB
      • MasterCard
      • Visa
      • English
      • Hindi
      • Spanish
      • Tagalog


      • Number of rooms: 4
      • Parking
      • Service Animals Allowed

      Hotel areas that are accessible:

      Guest Rooms

      Exercise Facility

      Concierge Desk

      Business Center


      Registration Desk

      Public Entrance

      Hotel areas with accessible routes from accessible public entrance:

      Exercise Facility

      Meeting Room/Ballroom Area

      Business Center

      Registration Desk

      Accessible Guest Rooms

      Hotel provides the following:

      Portable Tub Seats

      TTY for Guest Use

      Assistive Listening Devices for Meetings Upon Requests

      Closed Caption Televisions

      Accessible Self Parking

      Van Accessible Self Parking

      Number of Accessible Meeting Rooms: 2