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    Breakfast included
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    Check In: 3:00 PM  |  Check Out: 11:00 AM


      4000 Market Street, Hannibal
      (Includes VAT)
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      Welcome to Holiday Inn Express & Suites Hannibal

      Choose Our Pet-Free Hotel in Hannibal

      Welcome to the Holiday Inn Express® Hotel & Suites Hannibal located near Highway 61 in "America's Hometown," Hannibal, Missouri. Our hotel's sparkling, clean facility offers the name you trust, the services you deserve and a price to fit your budget.

      Business travelers appreciate our hotel's great Hannibal location near General Mills, Buckhorn, Enduro and all other factories in the industrial area. We offer corporate amenities like a business center that features copy, fax and print services, as well as free Wi-Fi access. There's also event space available for business seminars or meetings at our hotel. Hannibal business travelers make the smart choice when they choose us.

      Leisure patrons know that we're a cut above other hotels, with Hannibal city attractions, restaurants and shopping areas just minutes away. Historic downtown boasts the Mark Twain Home and Museum, and other interesting Twain related attractions, like Sawyer's Creek Fun Park, are less than three miles from our hotel. This Hannibal attraction is perfect for the kids and is located right across the street from Mark Twain Cave and Cameron Cave.

      Our friendly staff offers a 24-hour welcome to Mark Twain's Hometown and to our pet-free Holiday Inn Express® hotel in Hannibal, Missouri. Our hotel's clean facility is proud to offer a free, hot breakfast every morning, our brand new fitness center, an indoor pool and a whirlpool.

      Features Our Lowest Internet Rate Guarantee means you get the best deals & rates for hotels in Hannibal, Missouri. Our pet-free hotel's rooms are the cleanest and have terrific perks like free wireless and high speed internet access. The Hotel also has an indoor swimming pool and hot tub, and the excellent Express Breakfast Bar for a woderful smart start to your day.

      Business Services

      Wireless Data Connection
      Business Center

      Health and Fitness Center (On-site)

      Health/Fitness Center On-Site

      Health and Fitness Center (Off-site)

      Health/Fitness Center Off-Site

      Entertainment and Recreation

      Indoor Pool

      Housekeeping and Laundry Services

      Dry Cleaning Pickup or Laundry Valet

      Same Day Dry Cleaning


      Safety Deposit Box available at Front Desk

      ATM/Cash Machine

      Nearby Restaurants

      Location:  None
      Serves:  Lunch, Dinner
      For a good place to get a good steak, seafood, or just a drink! This is one of the newest additions to Hannibal Dinning, and the customers love it!
      Logue's Restaurant
      Location:  None
      Serves:  Breakfast, Lunch, Dinner
      A family style restaurant that you can dine in for home cooked favorites. They also have enough space for any groups that would like to come in at once, with advance reservations.
      Ole Planters Restaurant
      Location:  None
      Serves:  Lunch, Dinner
      Enjoy homemade food in the heart of the Hometown, just a quick walk from the Mark Twain Museum. This is a Hometown favorite in Hannibal, they are known for there Tenderloins and Salads.
      LaBinnah Bistro
      Serves:  Dinner
      For a nice quite meal, with all the trimmings,great for a romantic evening with the one you love, or to treat the family to something a little different. Try the newest restaurant in town, that the local's are calling outstanding.

      Guestroom data services

      Wireless Data Connection

      High-speed Internet Access

      Business Center data services

      Wireless Data Connection


      High-speed Internet Access

      Public space data services

      Wireless Data Connection

      High-speed Internet Access

      • Free Parking for hotel guest.
      • No Pet Policy for this hotel. If pet or evidence of pet is found a 50.00 charge will be applied to hotel folio for each night the pet is found in room.
      • American Express
      • Carte Blanche
      • Diners Club
      • Discover
      • JCB
      • MasterCard
      • Visa
      • English


      • Number of rooms: 4
      • Parking
      • Service Animals Allowed

      Hotel areas that are accessible:

      Guest Rooms

      Exercise Facility


      Concierge Desk

      Business Center

      Registration Desk

      Public Entrance

      Hotel areas with accessible routes from accessible public entrance:

      Exercise Facility

      Meeting Room/Ballroom Area


      Business Center

      Registration Desk


      Accessible Guest Rooms

      Hotel provides the following:

      Portable Tub Seats

      TTY for Guest Use

      Assistive Listening Devices for Meetings Upon Requests

      Communication Kits With Visual Alarms And Notification Devices

      Closed Caption Televisions

      Accessible Self Parking

      Van Accessible Self Parking

      Number of Accessible Meeting Rooms: 1