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    Breakfast included
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    Check In: 3:00 PM  |  Check Out: 11:00 AM

    Charleston Dwtn - Medical Area

      250 Spring Street, Charleston
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      ATTENTION Construction Alert: We want to notify all guests of the WestEdge Development, a neighboring construction project that will enhance the surrounding area. There is no construction on-site, however there is construction surrounding the property. Construction times vary and can be loud at times. Work can start at 7AM and continue into the evening. We apologize for any inconvenience.

      Welcome to Holiday Inn Express Charleston Dwtn - Medical Area

      Welcome to the Holiday Inn Express Charleston Downtown - Ashley River

      We are perfectly located near the Medical University of South Carolina and in close proximity to Charleston's Historic District. The Holiday Inn Express features a beautiful outdoor pool, Express Start hot breakfast buffet and free high-speed wireless internet. Just around the corner from us there is beautiful, dog-friendly Brittlebank Park with its state-of-the-art playground and fishing pier and within walking distance to Joe Riley Baseball Field, home of the Charleston Riverdogs. Plus, we are convenient to the Charleston area's many historic plantations, golf courses, and pristine beaches.

      Features We surpass other Charleston, SC hotels thanks to our terrific location. Being along the Charleston DASH Trolley route, getting to Historic Charleston is a breeze. And if you're here visiting the Medical University of South Carolina, we are within just a few blocks. We are within walking distance to the Joe Riley Stadium home to the Charleston Riverdogs!

      Business Services

      Wireless Data Connection
      Business Center

      Health and Fitness Center (On-site)

      Health/Fitness Center On-Site

      Health and Fitness Center (Off-site)

      Health/Fitness Center Off-Site

      Entertainment and Recreation

      Outdoor Pool

      Housekeeping and Laundry Services

      Daily Housekeeping

      Dry Cleaning Pickup or Laundry Valet

      Same Day Dry Cleaning


      Safety Deposit Box available at Front Desk

      Air Conditioning in Public Areas

      Ice Machine

      Concierge Services

      Don't miss our complimentary Express Start Hot Breakfast Bar each morning. Try our new pancake machine or signature cinnamon rolls, and wash it down with a cup of our freshly brewed 100% Arabica bean coffee.

      Guestroom data services

      Wireless Data Connection

      High-speed Internet Access

      Business Center data services

      Wireless Data Connection


      High-speed Internet Access

      Public space data services

      Wireless Data Connection

      High-speed Internet Access

      • Number of parking spaces:108
      • Free parking for hotel guests and overflow parking in adjacent lot at the rear of the hotel. Parking is limited to one vehicle per room. Parking permit issued upon checked-in. Motorcoach/tour bus parking avail at Visitor's Center - call for details.
      • MUST BOOK A PET FRIENDLY ROOM TYPE. ROOM TYPE NAME MUST SAY PET FRIENDLY: 2 pets max per room. 25 dollars per day with max of 150 dollars per stay. Pets must be crated when left alone in rooms. Dogs and cats only. Some breed restrictions.
      • 25.0 USD 
      • American Express
      • Carte Blanche
      • Diners Club
      • Discover
      • JCB
      • MasterCard
      • Visa
      • English
      • Japanese
      • Spanish


      • Number of rooms: 7
      • Parking
      • Service Animals Allowed

      Hotel areas that are accessible:

      Guest Rooms

      Exercise Facility


      Business Center

      Registration Desk

      Public Entrance

      Hotel areas with accessible routes from accessible public entrance:

      Exercise Facility

      Meeting Room/Ballroom Area


      Business Center


      Registration Desk

      Accessible Guest Rooms

      Hotel provides the following:

      TTY for Guest Use

      Communication Kits With Visual Alarms And Notification Devices

      Closed Caption Televisions

      Accessible Self Parking

      Van Accessible Self Parking

      Number of Accessible Meeting Rooms: 1